As weight loss medications like Ozempic and Mounjaro surge in popularity it’s important to understand the risks and links to your gut health that many people aren't aware of.
Constipation is a primary unexpected and unpleasant side effect of Ozempic and other weight loss drugs while another factor is the burden these drugs put on the liver.
Weight loss drugs place new demands on the body’s detoxification and digestive systems as they cause gastroparesis which can negatively impact your gut health.
Fortunately, natural support strategies like coffee enemas, probiotics and magnesium oxide supports such as Constaclear and Gut Food can help provide relief, restore balance and keep your gut and liver functioning optimally.
Why Ozempic Causes Constipation?
What is Ozempic and how does it impact your digestive system? Ozempic is a GLP-1 receptor agonist which works by mimicking a hormone that slows gastric emptying. It causes what is effectively known as gastroparesis (paralysis and slowing of the stomach and gastrointestinal tract) in order to reduce appetite and improve insulin sensitivity.
While this function supports weight loss and blood sugar control it can have damaging effects on your digestive system which can lead to bloating, constipation, poor digestion, acid reflux and abdominal distention and discomfort.
Constipation is one of the most common side effects reported by people using Ozempic and Munjaro, especially when the person had no bowel efficiency issues prior. When food moves more slowly through the gut, it can lead to harder stools, reduced bowel frequency, and a sluggish feeling. The weight loss medication also makes you feel fuller for longer and therefore which means people are not eating enough fibre or drinking as much water to bulk and move their stools through the colon.
Over time, constipation can have a counter-productive effect as the patients seeking weight loss now have a slow metabolic function from a slow bowel and may be carrying high amounts of stool in the gut making them feel sluggish, tired and more inclined to choose sugary foods.
Liver Health and GLP-1 Medications
Interestingly, emerging research suggests that GLP-1 drugs like Ozempic may offer some benefits for fatty liver disease for those losing weight, helping to reduce liver fat and improve metabolic markers. However, this doesn’t mean your liver is off the hook. The liver still plays a central role in processing medications, hormones, and toxins so supporting its function is essential, especially when introducing new pharmaceuticals.
Natural Constipation Relief Solutions
If you ever need to get constipation relief fast, the best and most effective home solution is an enema. Enemas have been used for centuries as a form of natural colon cleansing and can be done with water, organic coffee and herbal tea.
Coffee enemas have long been used in holistic integrative wellness to stimulate the liver and gallbladder, encouraging bile flow and detoxification. Coffee enemas stimulate the peristaltic motion in the gut and provide easy natural relief. For those on weight loss medications, they offer a powerful way to:
-
Relieve constipation by stimulating peristalsis and clearing the colon
-
Support liver detox pathways, helping process metabolic waste and medication byproducts
-
Reduce bloating and abdominal discomfort, especially when digestion slows
By introducing organic coffee rectally, the body absorbs compounds like cafestol and kahweol, which trigger the liver to produce more glutathione. This your body’s master antioxidant for detoxification and combating free radical cells. This is helpful for the immune system and lowering the toxic load.
Best Constipation Relief Supplement
Constaclear is a natural, non-habit-forming capsule formula designed to promote regularity without harsh laxatives. It uses the power of heavy magnesium oxide to soften stools and draw water into the bowel to encourage movement. Main benefits include:
-
Relieve constipation and bloating
-
Soften stools for easy passage
-
Complement the detoxifying effects of coffee enemas
For those using Ozempic or similar medications, Constaclear can be a daily support tool to maintain gut motility and prevent the buildup of waste that can burden the liver and ultimately prohibit weight loss.
Supporting Constipation and Liver Health Daily At Home
If you're navigating weight loss with GLP-1 medications, consider these holistic supports to your gut health and liver along the way:
- Hydration: Aim for 2–3L of filtered water daily to keep stools soft.
- Daily Constaclear: Take as directed to support regular elimination.
- Coffee Enemas 2–3x Weekly: Especially on days when digestion feels sluggish or bloating is present.
- Probiotics - 1 Scoop of Gut Food Daily for optimal gut balance
- Liver-Loving Herbs: Consider drinking Happy Liver Tea which contains Dandelion, Liquorice and Burdock Root, Nettle and Wolfberries.
- Movement: Gentle walking, yoga or rebounding helps stimulate lymphatic flow and digestion to prevent stagnation.
Weight loss medications like Ozempic can be transformative, but they’re not without side effects. By supporting your gut and liver naturally with tools like coffee enemas and Constaclear, you can enhance your results, reduce discomfort, and feel more empowered on your wellness journey.
If you're curious about how to integrate these practices into your lifestyle or want to explore a deeper detox protocol download the 21 day challenge or visit our constipation support relief page.
